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Frequently Prescribed Medications for Tricyclic Antidepressants
muscular weakness and concentration problems, and they
Fibromyalgia Tryptizol (Amitriptyline) is known for pain relieving
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effects and ability to help sleep. This medication should be
Serotonin Boosting Medications (SSRIs)
taken early in the evening or half dose in the evening and
TRICYCLIC ANTI-DEPRESSANTS
the other half at bedtime to avoid morning hangover.
Prozac (Fluoxetine) is available in liquid as well as tablet
Amitriptyline-Tryptizol Doxepin - Sinequan
form. Prozac may cause insomnia, but it can be taken in
Nortriptyline -Allegron
Trazadone- Molipaxin Sinequan (Doxepin) Also a tricyclic that functions in the
combination with one of the sedating tricyclics such as
body as an antihistamine. Available in both tablet and
BENZODIAZEPINES
Alprazolam – Xanax Seroxat (Paroxetine hydrochloride) This medication is the
Diazepam - Valium Allegron (Nortriptyline) is an antidepressant with a weak
most potent of this type. A sedating medication may be
sedative or stimulating property which may be useful in
needed at night in conjunction with Seroxat. It can cause
SEROTONIN- BOOSTING MEDICATIONS
people with severe fatigue. May help to lift depression
nervousness, insomnia, nausea, sexual difficulties and
quite quickly, but like all these tablets may also have
Fluoxetine – Proz Cipramil
Paroxetine – Seroxat Sertaline Sertaline (Lustral) is similar in action to Prozac being less
Escitalopram-Cipraflex
Venlafaxine-Efexor Molipaxin (Trazodone) is as effective as the other anti
sedative than the Tricyclic drugs and shouldn't cause
depressants, however, it is chemically different and may
MUSCLE RELAXANTS
be less likely to cause side effects. Molipaxin is a mild
Tizanadine - Zanaflex Baclofen Lioresal
stimulant and may make a sleep problem worse if
Prothiaden (Dothiepin hydorchloride). Similar to the
combined with a tricyclic anti-depressant at night
others, this drug is often given if anxiety plays a large role
Methocarbamol-Robaxin
in your Fibromyalgia. It has sedation as well as anti-
Benzodiazepines
depression properties. Dosages start low if given purely
ANALGESICS
(Anti-depressant and anti-anxiety properties)
Prescription medications at doctor’s discretion.
Efexor (Venlafaxine Hydrochloride) is not related to the Xanax (Alprazolam) May be more effective if taken with
tricyclics or the Prozac like drugs, however, it does boost
Ibuprofen. However, it may actually cause depression in
some individuals and may be addictive, but may also be
serotonin and has tricyclic properties. The typical side
effective in some cases of Fibromyalgia if taken in low
effects are nervousness, anxiety, insomnia, and increased
Valium (Diazepam) can be used for short-term treatment Muscle Relaxants
of anxiety states associated with insomnia or depression.
¿ These drugs are potentially addictive and if used frequently,
Normal dose rates are between 2 and 5 mg a day for those
Robaxin (Methocarbamol) is a muscle relaxant whose
with Fibromyalgia but may be higher if clinical depression
effects are not fully understood, but which may relax
cramped muscles. Robaxin may be taken in combination
ANTIEPILEPTIC DRUGS
with Tryptizol to provide maximum relief.
Lorezapam and Oxazepam are similar in effect to the
Must be used with caution for FMS purposes.
above and equally given in low doses initially to effect.
Norflex (Orphenadreine Citrate) is one to try if the patient
does not respond to Amitriptyline. It is a central acting
The anti-depressant and anti-anxiety properties of these
analgesic muscle relaxant that has been found to decrease
medications can cause the following effects: depression,
pain in some FMS patients. Norflex is most often taken at
drowsiness, impaired co-ordination, impaired memory,
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night, but some patients are able to tolerate this medication
further to try nor anything that will better alleviate your
pain. Because this is a chronic condition you need to
understand that there is a major issue about taking these
Patients should be cautioned that muscle relaxants can
types of drugs long term i.e. longer than 6 months. Please
cause drowsiness and they should not operate a motor
note that even strong analgesics may not always alleviate
vehicle when taking this type of medication. There are
other muscle relaxants to try if these do not work.
Topical Creams
Presently, no single medication alleviates all of a
NSAIDs (Anti-inflammatory Medications)
Fibromyalgia patient's pain and accompanying symptoms.
This makes it - doubly important for physicians to keep
Axsain cream (Capsaicin 0.075%) A topical analgesic that
updated regarding results of ongoing FMS research and
can be obtained either through a Pain Clinic or by
current changes In recommended fibromyalgia treatments.
prescription. Axsain is effective for relief of pain of
these anti-inflammatories have not proven
arthritis in specific areas and has been shown to help FMS
Before prescribing a medicine for a patient it is the
effective in reducing FMS pain, probably because there is
patients in a similar form in the US. It is suggested that it
classically little inflammation involved in the condition.
responsibility of the attending physician to elicit a
be used three to four times per day for maximum
comprehensive medical history. Because different
Amitriptyline and Xanax's effectiveness is
effectiveness. Axsain can be extremely irritating to the eye
symptoms accompany each FMS patent, the doctor - needs
increased when used in combination with Ibuprofen (2400
so hands should be washed well after application.
mg per day). If the patient has arthritis,
to know what problems are specific to each individual. For
tendonitis or any other inflammatory rheumatic condition,
Balmosa cream is composed of methyl salicylate,
non-restful sleep is almost always a major
concern for Fibromyalgia sufferers. Small doses, usually
these medications would be helpful in alleviating the pain.
camphor and menthol, and has helped reduce pain in some
10 mg, of an antidepressant seems to help many FMS
It should be noted that most of these medications can
cause stomach upset and some patients have developed
Another relatively new but excellent topical for muscle
It is important for the physician to encourage the patient to
bleeding ulcers. Exceptions would likely be the Celebrex
spasms, cramps etc is Biofreeze - available in some shops,
keep a detailed written journal of medicines,
possibly as this has a slightly different preparation (Cox-2
but can be obtained through FMSNI or on the internet.
timing and side effects. This record will be beneficial to
inhibitors). However, caution should be applied with all.
the patient as well as the doctor when writing a
Pharmacists may recommend other topical creams with
similar properties. There are many on the market that may
Analgesics
It takes time and communication between the health care
When first diagnosed most patients will usually be offered
professional -and patient to determine the correct FMS
an SSRI (see above) and a mild painkiller e.g. Paracetamol
proper dosages and appropriate time to take
or a paracetamol/codeine mix where the codeine
component is quite low. However, if you've had reason to
take a lot of painkillers in the past or your pain is pretty
FMSNI takes no responsibility for any adverse reactions Fibromyalgia Support N. Ireland
entrenched, you will most likely find that these aren't
found by taking any of the products listed in this brochure.
really effective. If so, it's worth discussing with your
doctor the option on at least a trial of something stronger.
If you show understanding of both your own condition and
ALWAYS DISCUSS MEDICATIONS SUPPORTLINE: 08709 909220
the difficulties of taking chronic pain relief, your GP
TAKEN WITH YOUR DOCTOR
should hopefully be willing to work with you to help you
obtain a better solution. Be aware though that bit by bit
TAKE THEIR ADVICE!
you may progress up the 'analgesic ladder' and obviously may reach a point where there really is neither anything
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Quote ref: MHS/11514 Internal Ref: LR/NW THE UNIVERSITY OF MANCHESTER PARTICULARS OF APPOINTMENT FACULTY OF MEDICAL AND HUMAN SCIENCES Respiratory Research Group Research Associate (Ref: MHS/11514) • The University invites applications for the above post which is tenable to 30 November 2013 • Salary will be within the range £28,983 - £34,607 per annum according to r
Akademisk avhandling Akademisk avhandling som för avläggande av ekonomie doktorsexamen vid Internationella som för avläggande av ekonomie doktorsexamen vid Internationella Handelshögskolan i Jönköping kommer att försvaras i sal B1014, Handelshögskolan i Jönköping kommer att försvaras i sal B1014, Internationella Handelshögskolan i Jönköping, fredagen den 7 mars 2008 kl.