Le tadalafil possède une affinité marquée pour la PDE5, mais épargne en grande partie les isoformes PDE1, PDE2 et PDE11, réduisant ainsi le risque d’effets extra-caverneux. L’action se traduit par une augmentation contrôlée de la circulation sanguine locale, indépendante des variations alimentaires. Sa pharmacocinétique repose sur une absorption digestive rapide, un métabolisme hépatique par CYP3A4 et une distribution tissulaire large. La biodisponibilité reste stable, et l’équilibre plasmatique est atteint en quelques jours lors d’administrations répétées. Les interactions cliniquement significatives surviennent avec les inhibiteurs puissants de CYP3A4 tels que le kétoconazole. Dans la littérature pharmacologique, acheter cialis 20 mg est souvent associé à des schémas d’utilisation basés sur la durée prolongée de son action.
Microsoft word - influenza-cold-aller.doc
Savel, Kelly, Boreman, & Odom M.D.’s
INFLUENZA
• Influenza or the flu is a severe viral infection of the respiratory tract. • It is extremely contagious through coughing & sneezing with an incubation
• Symptoms are much more severe than regular colds. • Fever is almost always present. It can start suddenly & may last 3-5 days. • There may be exhaustion or an overall feeling of tiredness & sleepiness. • Muscle aches are common even to where it is sore to move or touch. • Congestion, sneezing, coughing & watery eyes are present in both the flu and
colds. The flu commonly leads into chest congestion or pain.
• Headache is also present in the flu. • The flu can be prevented by getting a yearly FLU SHOT. TREATMENT:
• Antibiotics do not cure the flu. • Get lots of rest & fluids. Offer fever & pain relievers (Tylenol or Motrin) in
children older than 2 months for fever or any other physical discomfort.
• Also offer cough (Delsym) & cold medicines like antihistamines (Benadryl) to
• Apply Vaseline, or antibiotic ointment to nasal openings to prevent & cure
irritation or infection of the skin in the nasal area.
• Steam showers or a cool-mist humidifier in the bathroom will help to loosen
• Nasal saline drops & gentle suctioning may benefit infants & young children. • Cool compresses with damp towels or cloths help reduce fever. • If your child is old enough offer throat lozenges or warm salt-water gargle to
• REMEMBER TO WASH HANDS OFTEN TO PREVENT SPREAD! • The flu can be prevented by getting a yearly FLU SHOT.
Call or bring your child into the office IF:
• Fever is greater than 104 or lasts longer than 2-3 days. • Cough interferes with eating or sleeping & is not relieved with treatments. • Your child is breathing hard, wheezing or has noisy breathing. • Your child develops a rash or is extremely fussy. • Your child is very sleepy or inactive. • Your child is younger than 2 months. • Your child is not eating &/or not wetting diapers as often. • Symptoms last longer than 10 days. • You have any concerns or your child seems worse.
Savel, Kelly, Boreman, & Odom M.D.’s
FACTS ABOUT COLDS & ALLERGIES
• Colds are caused by one of hundreds of common viruses. • Easily passed from person to person by droplets from sneezing,
• Colds are not caused from cold air, getting wet or going outside. • Symptoms of a cold may be fever, headache, tiredness, fussiness,
stuffy nose, sneezing, watery eyes, sore throat or cough.
• There is no cure for a cold. Antibiotics do not work against colds. • Treatment is to keep your child comfortable with plenty of fluids &
pain relievers as needed in children older than 2 months.
• Treatment of symptoms, like cough & nasal congestion can be done
with saline nose drops or over-the counter cough/cold medicines like Delsym or Benadryl.
• Antibiotics may be used to treat bacterial complications of a cold
• To prevent colds, wash hands often & keep your distance from
• Please call the office if you have concerns about your child.
ALLERGIES (SEASONAL RHINITIS):
• Allergies are caused by airborne irritants or allergens that trigger
• Irritants like trees & grass pollens are common in the spring. • Irritants like ragweed pollen, dust & mold are common in the fall. • Symptoms of allergies may be runny or stuffy nose, itchy or watery
eyes, headache, sneezing or sore throat.
• Prevention is the best treatment. Avoid the allergens by keeping your
child indoors or showering/bathing at the end of the day. Cover mattresses & pillows with hypoallergenic covers.
• Treatment of symptoms with antihistamines like Benadryl at night or
non-sedating loraditine (Claritin or Alavert) for day symptoms may be helpful.
• Nasal congestion can also be treated with saline nose drops. • Antibiotics do not work against allergies. • People who have allergies are more prone to problems like ear, sinus
or chest infections. Antibiotics are sometimes used to treat these
• There are many types of prescription medicines used for allergies. • Please call the office if your child has persistent or severe symptoms.
Hip International / Vol. 12 no. 4, 2002 / pp. 383-387Early resection of heterotopic ossification after total hip arthroplasty: A review of the literatureDepartment of Orthopedics and Traumatology, Ghent University Hospital, Gent - Belgium ABSTRACT: Early excision of heterotopic ossification was performed in 8 patients at an average of 10.2 months after total hip arthroplasty. All patients re
• ED is a symptom of many underlying conditions • Endothelial dysfunction seems to be a common final pathway to ED in patients with hyperlipidemia, diabetes mellitus, hypertension, and chronic renal failure• The recognition of ED as a warning sign of silent vascular disease has led to the concept that a man with ED and no cardiac symptoms is a cardiac patient until proven otherwise