Microsoft word - common chemotherapeutic drugs used in the treatment of bre–

Common Chemotherapeutic Drugs Used in the Treatment of Breast Cancer
Generic (Brand)
Adverse Reactions
Manufacturer
*Not all patients will experience
Indications
Classification
Precautions
(Manufacturer’s website addresses are
provided when known)
Hormone antagonist Fetal harm to pregnant Nausea, vomiting, peripheral coagulation Diarrhea, vomiting, stomatitis, bleeding with coumarin. and foot syndrome, dermatitis, required. Contraindicated with severe renal impairment.
gallbladder disease and spotting, changes in menstrual http://www.nlm.nih.gov/medlineplus/druginfo mutagenesis, impairment of fertility, cardiac toxicity Pregnancy category D, Rash, neutropenia, leukopenia, toxicity deaths reported, anemia, fluid retention, in- severe fluid retention, fection, alopecia, nausea, Doxorubicin HCl (Adriamycin PFS and RDF) and many others antibiotics irreversible myocardial heart failure, alopecia, toxicity, bone marrow mucositis, fever, chills, Adjuvant therapy in Antitumor antibiotic Pregnancy cat D, Extravasation will cause hot flashes, nausea, vomiting, severe tissue necrosis, mucositis, diarrhea, anorexia, secondary AML, reduce leukopenia, neutropenia, http://www.solvaypharmaceuticals-us.com/ cancer endometrial cancer, use spotting, changes in menstrual http://www.patienteducation.com/exemestane tamoxifen therapy impairment, history of leukopenia, alopecia, dermatitis http://www.nursespdr.com/members/database high-dose pelvic irradiation or previous use of alkylating agents, avoid extravasation Antibody formation has headache, sweating, acne, pain breast cancer and prostatic carcinomaTreatment of Pregnancy cat D, Fetal Fatigue, chest pain, decreased Pregnancy cat D, Do not Thromboembolic phenomena use in first 4 months of such as thrombophlebitis and reported, bone marrow vomiting, diarrhea, myalgia, Adjunct therapy in Hormone antagonist Pregnancy cat C http://www.nlm.nih.gov/medlineplus/druginfodisseminated breast cancer Adenocarcinoma of Ankylating agent Pregnancy cat D, Death Fatigue, weakness, fever, rash, http://www.nursespdr.com/members/database cavities toxic to hemotopoietic system, Fetal harm thromboembolytic diseases. Vaginal bleeding ventricular dysfunction, ejection fraction, CHF, anemia, congestive heart failure leukopenia, diarrhea which overexpress HER2 proteins Advanced non- Granulocytopenia, local leukopenia, granu- thrombophlebitis with neuropathy, alopecia, nausea extravasation This information was compiled from the following sources:
Adams, Val R., et al., Guide to Cancer Chemotherapeutic Regimens, 2002, McMahon Publishing Group. American Cancer Society, Consumers Guide to Cancer Drugs, 2000, Jones and Bartlett Publishers, Inc. Lynch, Mary Pat, Oncology Nursing Essentials, 2002, Professional Publishing Group, Ltd. Mason, James, Oncology Digest: Therapeutic Reference Guide, 2001, Odontis Publishing, Inc. Medical Economics Company, PDR 2002, First Edition, Oncology Reference Guide, 2002, Medical Economics Company. Our thanks to Susan Lonon for compiling this list and to Anne Abate and Becky Rosen for editing.

Source: http://www.ibcresearch.org/Common_Chemo.pdf