Le tadalafil possède une affinité marquée pour la PDE5, mais épargne en grande partie les isoformes PDE1, PDE2 et PDE11, réduisant ainsi le risque d’effets extra-caverneux. L’action se traduit par une augmentation contrôlée de la circulation sanguine locale, indépendante des variations alimentaires. Sa pharmacocinétique repose sur une absorption digestive rapide, un métabolisme hépatique par CYP3A4 et une distribution tissulaire large. La biodisponibilité reste stable, et l’équilibre plasmatique est atteint en quelques jours lors d’administrations répétées. Les interactions cliniquement significatives surviennent avec les inhibiteurs puissants de CYP3A4 tels que le kétoconazole. Dans la littérature pharmacologique, acheter cialis 20 mg est souvent associé à des schémas d’utilisation basés sur la durée prolongée de son action.

Are you suprised ?

k=;+= k|zf;g ÷)&)÷)&! ldlt M— @)&).&.^ >L ;‹Lo dfldnf tyf :yfgLo ljsf; dGqfno k|:t't ljifodf o; sfof{nosf] g=kf= jf]8{n] ldlt @)&) ;fn cflZjg dlxgfdf u/]sf] lg0f{o ptf/ tkl;n adf]lhd /x]sf] Joxf]/f cg'/f]w 5 . ldlt @)&).^.!# ut]sf] g=kf= af]8{ a}7ssf] lg0f{o ptf/ gu/kflnsf af]8{ a}7s k|d'v Pj+ sfo{sf/L clws[t >L 6LsfbQ /fO{ Ho"sf] cWoIftfdf lgDg pkl:yltdf a:of] . lg0f{o g+= ! -Ps_ l;4fy{gu/ gu/kflnsf cGt{/ut ;~rflnt Plss[t zx/L ljsf; kl/of]hgfaf6 kmf]xf]/d}nf Joj:yfkgsf] nfuL gu/kflnsfsf] :jfldTjdf /x]sf] k6\vf}nL uf=lj=;= j8f g+= *.s sf] ls=g+= !^!* If]qkmn ^—)—) ljufxf hUufdf ;]g]6/L Nof08lkmn ;fO{6 lgdf{0f ug{sf] nfuL jftfj/0fLo k|efj d"NofÍg (EIA) ug{ Terms of Reference (TOR) / Scoping Document ;DalGw lgsfoaf6 :jLs[lt x'g DUDBC, IUDP cfof]hgf ;dGjo sfof{no (PCO) sf7df08f}+df k7fpg] lg0f{o ul/of] . lg0f{o g+= @-b'O{_ l;4fy{gu/ gu/kflnsfdf ;~rflnt IUDP Project sf] nfuL PlzofnL ljsf; a}+s / PCO 4f/f :jLs[t Project Administration Manual df Joj:yf eP cg';f/ o; l;=g=kf=df lgDg cg';f/sf] GESI UNIT u7g ug]{ lg0f{o ul/of] . M— >L u0f]z axfb'/ If]qL — j=c, l;=g=kf= l;4fy{gu/ gu/kflnsfdf PlzofnL ljsf; a}+ssf] C0f tyf cg'bfg ;xof]udf ;~rflnt Plss[t zx/L ljsf; kl/of]hgf cGt{ut xfn ;fn} :6n ul/Psf] Canon Image Prograf Plotter lk|G6/af6 ef}uf]lns gS;f+sg ;+u ;DalGwt ljleGg ;fO{hsf] /+lug gS;f lk|G6 x'g] ;'ljwf ePsf]n] ;/f]sf/jfnfx?n] gS;f dfu u/]df lgDgfg';f/ z'Ns lnO{ pknAw u/fpg] lg0f{o ul/of] . lg0f{o g+= $ -rf/_ l;4fy{gu/ gu/kflnsfdf ;+rflnt PsLs[t zx/L ljsf; kl/of]hgfsf] nflu @( clk|n @)!# df ;Demf}tf eO{ !% d] @)!# b]lv kl/rflnt ePsf] Design and Supervision Consultant (DSC) GOEC Nepal (P.) Ltd. JV with Technocrat Consultancy, New Baneshwor, Kathmandu af6 k|:tfljt e} 5gf}6 ePsf Solid Waste Management Engineer >L a|h lszf]/ rf}w/L / Social Safeguard Expert >L Pd= df:s]nfO{ x6fO{ (Replace) Solid Waste Management Engineer df >L l;=cf/= kf]v/]n / Social Safeguard Expert df >L lbks s'df/ ld>fnfO{ k|:tfj u/]sf]df d"Nof+sg ;ldltn] d"Nof+sg ubf{ klxn] 5gf}6 ePsf / clxn] k|:tfj ul/Psf lj1x?sf] c+s a/fa/ x'g cfPsf]n] xfn k|:tfj ul/Psf lgDg pDd]bjf/x?sf] lgDg cg';f/ c+s lgwf{/0f u/L kl/of]hgf ;dGjo sfof{no (PCO) tyf ADB df cfjZos ;xdltsf] nflu k7fpg d"Nof+sg ;ldltaf6 l;kmfl/; eO{ cfP cg';f/ :jLs[t ug]{ lg0f{o ul/of] . SUMMARY EVALUATION SHEET FOR FULL TECHNICAL PROPOSALS
Loan No.2851/Gra
nt 0284-NEP: Integrated Urban Development Project
Recruitment of Design and Supervision Consultants, Siddharthanagar
GOEC Nepal P. Ltd. JV with
LUATION CRITERIA
Technocrat Consultancy
I. Qualification
II. Approach and Met
hodology
III. Personnel (Areas of Expertise)
National Consultants
Road Construct ion / Utility Coordination Engineer Procurement an d Contract Management Specialist Rating: Excellent: 100% Very Good: 90 99% Above Average: 80 89% Average: 70 79% Below Average: 1 69% Non-complying: 0%
Score: Maximu m Weight x Rating / 100
CONFIDENT
PERSONNEL EVALUATION SHEET
Name of Firm: GO
EC Nepal P. Ltd. JV with Technocrat Consultancy
POSITION/AREA OF
EXPERTISE
Name of Firm: GOEC Nepal (P.) Ltd. JV with
Technocrat Co
nsultancy
Rating: Excell
ent: 100% Very Good: 90 99% Above Average: 80 89% Average: 70 79% Below Average: 1 69% Non-complying: 0% Score: Rating x percentage assigned to criterion
D:\ADM\Admintration\nirnay utar Mld\Nirnay utar_mlad_Ashbin_ 2070.docx ÆPs 3/ Ps rkL{ glhs}df wf/f, v'Nnf lbzf d'Qm gu/ agfpF xfdL ldnL ;f/fæ – l;4fy{gu/ gu/kflnsf kmf]g g+= M %@)#%%, %@)()*, %@)@(@, ˆofS; M ))(&&–&!–%@)!^% e-mail: siddhartha_bhw@ntc.net.np; http/:www.siddharthanagar.org.np Comparision of Evaluation of Proposed Expert for Replacement With Existing Expert
D:\ADM\Admintration\nirnay utar Mld\Nirnay utar_mlad_Ashbin_ 2070.docx ÆPs 3/ Ps rkL{ glhs}df wf/f, v'Nnf lbzf d'Qm gu/ agfpF xfdL ldnL ;f/fæ – l;4fy{gu/ gu/kflnsf kmf]g g+= M %@)#%%, %@)()*, %@)@(@, ˆofS; M ))(&&–&!–%@)!^% e-mail: siddhartha_bhw@ntc.net.np; http/:www.siddharthanagar.org.np

Source: http://www.siddharthanagar.org.np/uploaded/Nirnay%20utar_mlad_Ashbin_%202070.pdf