Le tadalafil possède une affinité marquée pour la PDE5, mais épargne en grande partie les isoformes PDE1, PDE2 et PDE11, réduisant ainsi le risque d’effets extra-caverneux. L’action se traduit par une augmentation contrôlée de la circulation sanguine locale, indépendante des variations alimentaires. Sa pharmacocinétique repose sur une absorption digestive rapide, un métabolisme hépatique par CYP3A4 et une distribution tissulaire large. La biodisponibilité reste stable, et l’équilibre plasmatique est atteint en quelques jours lors d’administrations répétées. Les interactions cliniquement significatives surviennent avec les inhibiteurs puissants de CYP3A4 tels que le kétoconazole. Dans la littérature pharmacologique, acheter cialis 20 mg est souvent associé à des schémas d’utilisation basés sur la durée prolongée de son action.

Cms formulary id: «cms_formulary_id»

Alliance CompleteCare
Future Formulary Change File
CMS FORMULARY ID: 13348
EFFECTIVE DATE: 6/1/2013

DRUG NAME
DILANTIN 50 MG ORAL

CHANGE DESCRIPTION
BRAND DELETION, ADD FRF GENERIC

REASON DESCRIPTION
REMOVAL OF BRAND NAME DRUG FROM FORMULARY DUE TO ADDITION OF NEW
GENERIC EQUIVALENT.

OTHER POSSIBLE DRUGS
Alliance CompleteCare
Future Formulary Change File
CMS FORMULARY ID: 13348
EFFECTIVE DATE: 6/1/2013

DRUG NAME
DUETACT 30 MG-2 MG ORAL

CHANGE DESCRIPTION
BRAND DELETION, ADD FRF GENERIC

REASON DESCRIPTION
REMOVAL OF BRAND NAME DRUG FROM FORMULARY DUE TO ADDITION OF NEW
GENERIC EQUIVALENT.

OTHER POSSIBLE DRUGS
Alliance CompleteCare
Future Formulary Change File
CMS FORMULARY ID: 13348
EFFECTIVE DATE: 6/1/2013

DRUG NAME
DUETACT 30 MG-4 MG ORAL

CHANGE DESCRIPTION
BRAND DELETION, ADD FRF GENERIC

REASON DESCRIPTION
REMOVAL OF BRAND NAME DRUG FROM FORMULARY DUE TO ADDITION OF NEW
GENERIC EQUIVALENT.

OTHER POSSIBLE DRUGS
Alliance CompleteCare
Future Formulary Change File
CMS FORMULARY ID: 13348
EFFECTIVE DATE: 6/1/2013

DRUG NAME
GRIS-PEG 250 MG ORAL

CHANGE DESCRIPTION
BRAND DELETION, ADD FRF GENERIC

REASON DESCRIPTION
REMOVAL OF BRAND NAME DRUG FROM FORMULARY DUE TO ADDITION OF NEW
GENERIC EQUIVALENT.

OTHER POSSIBLE DRUGS
Alliance CompleteCare
Future Formulary Change File
CMS FORMULARY ID: 13348
EFFECTIVE DATE: 6/1/2013

DRUG NAME
PROTONIX IV 40 MG INTRAVEN.

CHANGE DESCRIPTION
BRAND DELETION, ADD FRF GENERIC

REASON DESCRIPTION
REMOVAL OF BRAND NAME DRUG FROM FORMULARY DUE TO ADDITION OF NEW
GENERIC EQUIVALENT.

OTHER POSSIBLE DRUGS
Alliance CompleteCare
Future Formulary Change File
CMS FORMULARY ID: 13348
EFFECTIVE DATE: 6/1/2013

DRUG NAME
TRICOR 145MG ORAL

CHANGE DESCRIPTION
BRAND DELETION, ADD FRF GENERIC

REASON DESCRIPTION
REMOVAL OF BRAND NAME DRUG FROM FORMULARY DUE TO ADDITION OF NEW
GENERIC EQUIVALENT.

OTHER POSSIBLE DRUGS
Alliance CompleteCare
Future Formulary Change File
CMS FORMULARY ID: 13348
EFFECTIVE DATE: 6/1/2013

DRUG NAME
TRICOR 48 MG ORAL

CHANGE DESCRIPTION
BRAND DELETION, ADD FRF GENERIC

REASON DESCRIPTION
REMOVAL OF BRAND NAME DRUG FROM FORMULARY DUE TO ADDITION OF NEW
GENERIC EQUIVALENT.

OTHER POSSIBLE DRUGS
Alliance CompleteCare
Future Formulary Change File
CMS FORMULARY ID: 13348
EFFECTIVE DATE: 6/1/2013

DRUG NAME
ZERIT 1 MG/ML ORAL

CHANGE DESCRIPTION
BRAND DELETION, ADD FRF GENERIC

REASON DESCRIPTION
REMOVAL OF BRAND NAME DRUG FROM FORMULARY DUE TO ADDITION OF NEW
GENERIC EQUIVALENT.

OTHER POSSIBLE DRUGS

Source: https://www.alamedaalliance.org/~/media/files/modules/publications/pharmacy/2013%20acc%20pharmacy%20documents/future%20formulary%20change_june%202013.pdf