Microsoft word - equinedeworming

Deworming your horse: The inside story
Introduction
Internal parasites can have a negative effect on your horse, particularly in the young, growing animal and the older horse or pregnant mare. While horses can tolerate low levels of internal parasitism, an increased worm burden can cause ill thrift, weight loss, diarrhoea, colic, peritonitis or even pneumonia (secondary to migrating larvae). Deworming is an integral part of horse ownership however, in recent times, the overuse or the inappropriate use of commercially available anthelmintics (dewormers) has led to populations of parasites that are resistant to these chemical dewormers. Common Internal Parasites
There are numerous species of worms that can infect horses and several of these are of significance in Australia. These include roundworms (or ascarids, Parascaris equorum), large (Strongylus spp) and small (cyathostomes) strongyles, and tapeworms (Anoplocephala spp). Threadworm (Strongyloides westeri) infections are typically temporary and occur only in foals. Other common parasites of horses are pinworms (Oxyuris equi), and bots (the immature or larval form of adult botflies, including Gasterophilus intestinalis). Parasite Control
Chemical dewormers are readily available from veterinarians, pet stores and online. Despite a wide array of commercially available products with a variety of trade names, there are actually only a few licensed ingredients that can be used in horse wormers. This can contribute to resistant worm burdens as horse owners can be confused, believing they are using a different dewormer when in fact it is the same wormer only with a different trade name. Not all dewormers are effective against all types of worms. The main anthelminitcs available are as follows. o Ivermectin - targets all parasites except tapeworms and is effective against some
o Moxidectin - targets all parasites except tapeworms and is partially effective against
o Fenbendazole - targets large and small strongyles, pinworms, and roundworms and
it is effective against migrating strongyle larvae and encysted small strongyles when used at double the normal dose for five consecutive days; o Oxibendazole - targets large and small strongyles, pinworms, roundworms, and
o Pyrantel pamote- targets large and small strongyles, pinworms, roundworms, and
when used at a double dose will kill tapeworms (pyrantel formulations do not have action against encysted or migrating worms); o Praziquantel – targets tapeworms only
Currently, there are no studies to prove the effectiveness of any herbal medicine commercially available for treating equine internal parasites. Collecting manure from pasture on a regular basis (every day/alternate days) can reduce the chance of your horse picking up worm eggs from the faeces. Rotating paddocks, particularly after deworming your horse, can reduce the risk of reinfection with internal parasites. Feeding horses in proper feeders off the ground will reduce the intake of parasite eggs off the grass. Adequate time and an appropriate mixture of greens and browns is important if you are composting your horse’s manure. It is critical to make sure the compost is “cooked” properly so that parasite eggs are not reintroduced back onto the pasture. Anthelmintic resistance is defined as the development of populations of internal parasites that are not killed after recommended doses of anthelminitc drugs. Over dosing, under dosing and inappropriate scheduling of anthelmintic treatments have been cited as causes of anthelmintic resisitance in horses. To find out which anthelminitic is appropriate for your horses, a faecal egg count (FEC) should be carried out by your veterinarian. Your veterinarian can then determine which anthelmintic, how often you use it and what other strategies you can use to help decrease the worm burden in your horses. Resistance is a growing concern and steps we take now could make life in the future a lot less difficult. Deworming is an essential part of horse ownership. To carry out this task effectively it is important to discuss your situation with your veterinarian and to carry out some basic tests on your horses (FEC). Using a dewormer inappropriately could be more detrimental that not using a dewormer at all. Different populations of horses have different deworming requirements (foals, yearlings, mares, aged horses) and with the help of your veterinarian you can find out which strategy best suits your needs.

Source: http://www.bvp.com.au/library/file/167/factsheetdeworming.pdf

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A Pesquisa Operacional e o Desenvolvimento Sustentável CONTROLE DE QUALIDADE NA PRODUÇÃO DE CÁPSULAS DE OMEPRAZOL 20 MG Fernanda Karine Ruiz Colenghi Marta Afonso Freitas A indústria farmacêutica brasileira atende os regulamentos especificados pela ANVISA (Agência Nacional de Vigilância Sanitária), empresa responsável pelo controle sanitário de medicamentos. Para atende

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