Material Safety Data Sheet
Personal Protective Equipment
Health Hazard
Fire Hazard
Section 1. Chemical Product and Company Identification
Page Number: 1
Common Name/
Lidocaine Hydrochloride monohydrate
Trade Name
14422 S. SAN PEDRO STREET L i d o c a i n e H y d r o c h l o r i d emonohydrate Commercial Name(s)
Diethylamino-2,6-dimethylacetanilide hydrochloride monohydrate IN CASE OF EMERGENCY
Chemical Name
CHEMTREC (24hr) 800-424-9300
Chemical Family
Chemical Formula
14422 S. SAN PEDRO STREETGARDENA, CA 90248 Section 2.Composition and Information on Ingredients
Exposure Limits
TWA (mg/m3)
STEL (mg/m3)
CEIL (mg/m3)
% by Weight
Toxicological Data
Lidocaine Hydrochloride monohydrate:
on Ingredients
Section 3. Hazards Identification
Potential Acute Health Effects Very hazardous in case of ingestion. Hazardous in case of skin contact (irritant), of eye contact (irritant), of
inhalation. Slightly hazardous in case of skin contact (permeator).
Potential Chronic Health
The substance is toxic to the nervous system.
Repeated or prolonged exposure to the substance can produce target organs damage.
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Lidocaine Hydrochloride monohydrate
Page Number: 2
Section 4. First Aid Measures
Eye Contact
Check for and remove any contact lenses. Do not use an eye ointment. Seek medical attention.
Skin Contact
After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skinwith running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.
Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminatedclothing before reusing.
Serious Skin Contact
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediatemedical attention.
Allow the victim to rest in a well ventilated area. Seek immediate medical attention.
Serious Inhalation
Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possibleindication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosentight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouthresuscitation. Seek immediate medical attention.
Serious Ingestion
Section 5. Fire and Explosion Data
Flammability of the Product
May be combustible at high temperature.
Auto-Ignition Temperature
Flash Points
Flammable Limits
Products of Combustion
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2.), halogenated compounds.
Fire Hazards in Presence of
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
of Various Substances
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media
SMALL FIRE: Use DRY chemical powder.
and Instructions
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on
Fire Hazards
Special Remarks on Explosion Not available.
Section 6. Accidental Release Measures
Small Spill
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning byspreading water on the contaminated surface and dispose of according to local and regional authorityrequirements.
Large Spill
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading wateron the contaminated surface and allow to evacuate through the sanitary system.
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Lidocaine Hydrochloride monohydrate
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Section 7. Handling and Storage
Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate theresidue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust.
Wear suitable protective clothing In case of insufficient ventilation, wear suitable respiratory equipment Ifingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyesKeep away from incompatibles such as oxidizing agents.
Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightlyclosed. Keep in a cool, well-ventilated place. Combustible materials should be stored away from extreme heatand away from strong oxidizing agents.
Section 8. Exposure Controls/Personal Protection
Engineering Controls
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels belowrecommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure toairborne contaminants below the exposure limit.
Personal Protection
Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spill
to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialistBEFORE handling this product.
Exposure Limits
Section 9. Physical and Chemical Properties
Physical state and appearance
Molecular Weight
pH (1% soln/water)
Boiling Point
Melting Point
Critical Temperature
Specific Gravity
Vapor Pressure
Vapor Density
Odor Threshold
Water/Oil Dist. Coeff.
Ionicity (in Water)
Dispersion Properties
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Lidocaine Hydrochloride monohydrate
Page Number: 4
Section 10. Stability and Reactivity Data
Instability Temperature
Conditions of Instability
Incompatibility with various
Special Remarks on
Special Remarks on
Section 11. Toxicological Information
Routes of Entry
Toxicity to Animals
Acute oral toxicity (LD50): 220 mg/kg [Rat].
Chronic Effects on Humans
The substance is toxic to the nervous system.
Other Toxic Effects on
Very hazardous in case of ingestion.
Hazardous in case of skin contact (irritant), of inhalation.
Slightly hazardous in case of skin contact (permeator).
Special Remarks on
Toxicity to Animals
Special Remarks on
Chronic Effects on Humans
Special Remarks on other
Toxic Effects on Humans
Section 12. Ecological Information
BOD5 and COD
Products of Biodegradation
Possibly hazardous short term degradation products are not likely. However, long term degradation products mayarise.
Toxicity of the Products
The products of degradation are more toxic.
of Biodegradation
Special Remarks on the
Products of Biodegradation
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Lidocaine Hydrochloride monohydrate
Page Number: 5
Section 13. Disposal Considerations
Waste Disposal
Section 14. Transport Information
DOT Classification
Not a DOT controlled material (United States).
Special Provisions for
DOT (Pictograms)
Section 15. Other Regulatory Information and Pictograms
Federal and State
TSCA 8(b) inventory: Lidocaine Hydrochloride monohydrate Regulations
Proposition 65

Other Regulations
OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
Other Classifications
WHMIS (Canada)
CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
R22- Harmful if swallowed.
R36/38- Irritating to eyes and skin.
Health Hazard
National Fire Protection
Fire Hazard
Association (U.S.A.)
Personal Protection
Specific hazard
WHMIS (Canada)

DSCL (Europe)

TDG (Canada)

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Lidocaine Hydrochloride monohydrate
Page Number: 6
ADR (Europe)

Protective Equipment
Dust respirator. Be sure to use anapproved/certified respirator orequivalent. Wear appropriate respiratorwhen ventilation is inadequate.
Section 16. Other Information
Other Special
Validated by Sonia Owen on 1/20/2003.
Verified by Sonia Owen.
Printed 1/21/2003.
CALL (310) 516-8000
Notice to Reader
All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is
combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper methods
of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products, Inc. assumes
no responsibility for the completeness or accuracy of the information contained herein.

Source: http://www.dermalsource.net/pdfs/Lidocaine.pdf

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