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2010

Publikationen Prof. Dr. med. Stephan Miehlke
2013
Miehlke S
, Madisch A, Kupcinskas L, Petrauskas D, Heptner G, Böhm G, Dr. (5), Marks HJ,
Neumeyer M, Nathan T, Fernández-Bañares F, Greinwald R, Mohrbacher R, Vieth M,
Bonderup OK. Randomized, Placebo-controlled Multicenter Study of Budesonide and
Mesalamine for Short-term Treatment of Collagenous Colitis. JAMA 2013, eingereicht
Miehlke S, Aust D, Madisch A. Mikroskopische Kolitis - neue praxisrelevante Erkenntnisse.
Z Gastroenterol 2013, eingereicht
Von Arnim U, Miehlke S, Madisch A , Straumann A, Vieth M, Malfertheiner P. . Eosinophile
Ösophagitis –Neues zur Pathogenese, Diagnostik und Therapie. Z Gastroenterol 2013,
eingereicht

Miehlke S.
Mikroskopische Kolitis. Med Welt 2013;64:XX-XX
Miehlke S.
Ösophagus/Magen/Duodenum. In: Handbuch Gastroenterologie 2013.
Herausgeber: C. Ell, W. Fischbach, P. Layer, H. Zirngibl. ISBN 978-3-86302-067-5 med
publico GmbH.
Miehlke S, Alpan O, Schröder S, Straumann A. Induction of Eosinophilic Esophagitis by
Sublingual Immunotherapy. Allergy 2013, eingereicht

2012

Miehlke S, Madisch A. Eosinophile Ösophagitis. In: Miehlke S: Topische Steroide in der
Gastroenterologie, UNI-MED Bremen 2012, 1. Auflage, ISBN 978-3-8374-1361-8.
Madisch A, Miehlke S. Mikroskopische Kolitis. In: Miehlke S: Topische Steroide in der
Gastroenterologie, UNI-MED Bremen 2012, 1. Auflage, ISBN 978-3-8374-1361-8.
Miehlke S. A novel treatment algorithm for microscopic colitis. In: Microscopic colitis –
creating awareness for an underestimated disease. Editors: S. Miehlke, A. Münch, Falk
Workshop Basel 2012, p61-65.
Miehlke S. Therapy. In: Microscopic Colitis. 1. Edition, UNI-MED 2012, Bremen (Editor: A.
Tromm); ISBN 978-3-8374-1354-0.
Alpan O, Miehlke S, Straumann A. Oral immunotherapy for egg allergy in children. N Engl J
Med 2012;367:1472
Münch A, Aust D, Bohr J, Bonderup O, Fernández Bañares F, Hjortswang H, Madisch A,
Munck LK, Ström M, Tysk C, Miehlke S. Microscopic Colitis: current status, present and
future challenges - Statements of the European Microscopic Colitis Group. J Crohn’s Colitis
2012;6:932-45.
Miehlke S, Reinhold B, Schröder S. Successful treatment of Lichen planus esophagitis with
topical Budesonide. Z Gastroenterol 2012;50:1104-7.
Miehlke S, Hansen JB, Madisch A, Schwarz F, Kuhlisch E, Morgner A, Teglbjaerg PS, Vieth
M, Aust D, Bonderup OK. Risk factors for Symptom Relapse in Collagenous Colitis treated
with Budesonide. Inflamm Bowel Dis 2012, submitted.

Madisch A, Miehlke S, Bartosch F, Bethke B, Stolte M. Microscopic colitis: Clinical
presentation, treatment and outcome of 494 patients. J Crohn’s Colitis 2012, submitted
Schmelz R, Bornhäuser M, Ehninger G, Greinwald R, Müller R, Miehlke S. Randomized,
double-blind, placebo-controlled trial of budesonide for prophylaxis of intestinal graft-versus-
host disease (PROGAST). Submitted

2011

Miehlke S, Aust D, Morgner A, Baretton G, Madisch A. Probe-based Confocal Laser
Endomicroscopy in Double Balloon Enteroscopy. Z Gastroenterol 2011,49:1529-34.

Miehlke S
, Krasz S, Schneider-Brachert W, Kulisch E, Berning B, Madisch A, Laaß M,
Neumeyer M, Jebens C, Zekorn C, Knoth H, Jacobs E, Vieth M, Stolte M, Lehn N, Morgner A.
Randomized Multicenter Study of Esomeprazole, Moxifloxacin and Amoxicillin for Second-
Line or Rescue Treatment of Helicobacter pylori Infection. Helicobacter 2011;16:420-6.
Krasz S, Miehlke S, Berning M, Labenz J. Aktueller Stellenwert der Fluorochinolone in der
Therapie der Helicobacter pylori Infektion. Z Gastroenterol 2011;49:989-96

Miehlke S
, Löbe S, Madisch A, Kuhlisch E, Laass M, Grossmann D, Knoth H, Morgner A,
Labenz J. Aliment Pharmacol Ther 2011;33:471-6.
Berning M, Krasz S, Miehlke S. Should quinolones come first in Helicobacter pylori therapy?
Therap Adv Gastroenterol 2011;4:103-14
Miehlke S. Therapie. In: Mikroskopische Kolitis. 2. Auflage, UNI-MED Bremen (Hrsg. A.
Tromm) 2011, (ISBN 978-3-8374-1333-5).
Madisch A, Hellmig S, Schreiber S, Bethke B, Stolte M, Miehlke S. Inflamm Bowel Dis.
2011 Feb 8. doi: 10.1002/ibd.21640

Miehlke S.
Differentialdiagnose Ösophagitis: Eosinophile Ösophagitis, Candida,
Cytomegalievirus. Viszeralmedizin 2011;27:121-5.

2010

Pardi DS, Miehlke S. Microscopic colitis. In: Frontiers of Gastrointestinal Research, Editor:
M.M. Lerch: Clinical Update on Inflammatory Disorders of the Gastrointestinal Tract, Editors:
H. Tilg and J. Mayerle, Karger Verlag, Basel, 2010.
Bajbouj M, Vieth M, Rösch T, Miehlke S, Becker V, Anders M, Pohl H, Madisch A, Schuster
T, Schmid RM, Meining A.
, , , , , , , , , , . The safety of intravenous fluorescein for confocal laser endomicroscopy in the 2010;31:548-52. Distler M, Kersting S, Rueckert F, Dobrowolski F, Miehlke S, Grützmann R, Saeger HD.
Palliative treatment of obstructive jaundice in patients with carcinoma of the pancreatic head
or distal biliary tree: endoscopic stent placement vs. hepaticojejunostomy. J Pankreas
2010;11:1001-7.
Berning M, Krasz S, Labenz J, Miehlke S. Moderne Helicobacter pylori-Therapie in Zeiten
zunehmender Anitbiotikaresistenz. Med Klinik 2010;105:787-91

2009

Miehlke S, Madisch A, Karimi D, Wonschik S, Kuhlisch E, Beckmann R, Morgner A, Mueller
R, Greinwald R, Seitz G, Baretton G, Stolte
2009;136:2092-100.

Miehlke S
. Ösophagus-Magen-Duodenum. In: Handbuch Gastroenterologie 2009.
GastroUpdate. Reihe: , Med Update GmbH (Hrsg.) 2009, X, 380
S., Ringordner, ISBN: 978-3-642-00113-0.
Hofbauer LC, Miehlke S. N Engl J Med 2009;360:1790.
Bajbouj M, Becker V, Eckel F, Miehlke S, Pech O, Prinz C, Schmid RM, Meining A. Gastroenterology 2009;137:440-4.
Fischbach W, Malfertheiner P, Hoffmann JC, Bolten W, Bornschein J, Götze O, Höhne W,
Kist M, Koletzko S, Labenz J, Layer P, Miehlke S, Morgner A, Peitz U, Preiss JC, Prinz C,
Rosien U, Schmidt WE, Schwarzer A, Suerbaum S, Timmer A, Treiber G, Vieth Z Gastroenterol
2009;47:68-102.

Alberty J, Bisdas S, Issing PR, Kisch C, Madisch A, Miehlke S, Reiß G, Reiß M, Vogl TJ.
Ösophagus. In: Facharztwissen HNO-Heilkunde. Herausgeber. M. Reiß, Springer Medizin
Verlag Heidelberg 2009.
Fischbach W, Malfertheiner P, Hoffmann JC, Bolten W, Bornschein J, Götze O, Höhne W,
Kist M, Koletzko S, Labenz J, Layer P, Miehlke S, Morgner A, Peitz U, Preiss J, Prinz C,
Rosien U, Schmidt W, Schwarzer A, Suerbaum S, Timmer A, Treiber G, Vieth M; German
society for hygiene and microbiology; German society for pediatric gastroenterology and

Z Gastroenterol 2009;47:1230-63.

2008
Miehlke S
, Madisch A, Bethke B, Morgner A, Kuhlisch E, Henker C, Vogel G, Andersen M,

2008;135:1510-6.

Miehlke S,
Schneider-Brachert W, Morgner A, Madisch A, Kirsch C, Haferland C, Bästlein E,
Jebens C, Zekorn C, Knoth H, Stolte M, Lehn N. One-week once-daily triple therapy with
esomeprazole, moxifloxacin and rifabutin is effective an effective rescue treatment for
persistent Helicobacter pylori resistant to both metronidazole and clarithromycin.
Helicobacter 2008;13.69-74.
Miehlke S. Therapie. In: Mikroskopische Kolitis. 1. Auflage, UNI-MED Bremen 2008 (Hrsg.
A. Tromm); ISBN 978-3-8374-1044-0.
Madisch A, Morgner A, Stolte M, Miehlke S. Expert Opin Investig Drugs 2008;17:1829-37.
Rugge M, Kim JG, Mahachai V, Miehlke S, Pennelli G, Russo VM, Perng CL, Chang FY,
Tandon RK, Singal DK, Sung JJ, Valenzuela JE, Realdi G, Dore MP, Graham Int J Surg Pathol
2008;16:150-4.
Halank M, Langner S, Kolditz M, Miehlke S, Höffken G. Z Gastroenterol 2008;46:1260-5.
Madisch A, Schmolders J, Brückner S, Aust D, Miehlke S. Endoscopy 2008;40:731-4.
Grützmann R, Molnar B, Pilarsky C, Habermann JK, Schlag PM, Saeger HD, Miehlke S,
Stolz T, Model F, Roblick UJ, Bruch HP, Koch R, Liebenberg V, Devos T, Song X, Day RH,
Sledziewski AZ, Lofton-Day C 2008;3:e3759.


2007

Miehlke S, Morgner A, Aust D, Madisch A, Vieth M, Baretton G. Combined use of Narrow
band Imaging Magnification Endoscopy and Miniprobe Confocal laser Microscopy in
Neoplastic Barrett’s Esophagus. Endoscopy 2007, UCTN, 39: E1.
Miehlke S, Morgner A, Brückner S, Madisch A. APC treatment for small bowel
angiodysplasias. In: Atlas of Double Ballon Enteroscopy; 2007:45-47. Editor: C.J.J. Mulder,
Medconnect GmbH, Munich, Germany.
Miehlke S, Madisch A, Aust D, Morgner A, Laniado M, Saeger HD, Brückner S. Complicated
localized small bowel Crohn’s disease. In: Atlas of Double Ballon Enteroscopy; 2007:23-24.
Editor: C.J.J. Mulder, Medconnect GmbH, Munich, Germany.

Miehlke S, Madisch A, Aust DE, Morgner A, Saeger HD, Brückner S. Resection of Peutz-
Jeghers polyps. In: Atlas of Double Ballon Enteroscopy; 2007:75-77. Editor: C.J.J. Mulder,
Medconnect GmbH, Munich, Germany.

Miehlke S
, Brückner S, Aust D, Morgner A, Laniado M, Sinkwitz KD, Madisch A. Difficult
differential diagnosis of small bowel Crohn’s disease. In: Atlas of Double Ballon Enteroscopy;
2007:21-22. Editor: C.J.J. Mulder, Medconnect GmbH, Munich, Germany.
Miehlke S, Brückner S, Aust D, Morgner A, Madisch A. Retrieval of video capsules. In: Atlas
of Double Ballon Enteroscopy; 2007:121-122. Editor: C.J.J. Mulder, Medconnect GmbH,
Munich, Germany.
Madisch A, Miehlke S, Eichele O, Mrwa J, Bethke B, Kuhlisch E, Bästlein E, Wilhelms G,
Morgner A, Wigginghaus B, Stolte M. Boswellia serrata extract for the treatment of
collagenous colitis. A double-blind, randomized, placebo-controlled, multicenter trial. Int J
Colorec Dis 2007, Sep 2; [Epub ahead of print].
Morgner A, Miehlke S, Labenz J. Esomeprazole: Prevention and Treatment of Non-Steroidal
Anti-Inflammatory Drug (NSAID) - induced Symptoms and Ulcers. Exp Opin Pharmacother
2007;8:975-88.
Collet PH, Miehlke S. Blutstillung. In: Interventionelle Endoskopie – Lehrbuch und Atlas.
Herausgeber: Kahl S, Kähler G, Dormann A. Elsevier GmbH, Urban & Fischer Verlag,
München. 1. Auflage 2007.
Schmelz R, Miehlke S, Thiede C. Molekulare Pathogenese gastrointestinaler Lymphome.
Verdauungskrankheiten 2007;6:248-56.
Morgner A, Stolte M, Miehlke S. Visualization of lymphoepithelial lesions in gastric MALT-
type lymphoma by miniprobe confocal laser microscopy. Clin Gastroenterol Hepatol 2007,
5:e39.

Morgner A, Schmelz R, Thiede C, Stolte M, Miehlke S. Therapy of Gastric MALT lymphoma.
World J Gastroenterol 2007;13: 242-251.
Schwarz U, Hanso H, Oertel R, Miehlke S, Kuhlisch E, Glaeser H, Hitzl M, Dresser GK, Kim
RB, Kirch W. Induction of Intestinal P-glycoprotein by St. John’s Wort Reduces the Oral
Bioavailability of Talinolol. Clin Pharmacol Ther 2007; Mar 28; [Epub ahead of print].
Madisch A, Grützmann R, Aust D, Saeger HD, Ehninger G, Miehlke S. Acute bleeding in
jejunal GIST. In: Atlas of Double Ballon Enteroscopy; 2007:96-97. Editor: C.J.J. Mulder,
Medconnect GmbH, Munich, Germany.

2006
Miehlke S,
Hansky K, Schneider-Brachert W, Kirsch C, Morgner A, Madisch A, Kuhlisch E,
Bästlein E, Heptner G, Haferland C, Jacobs E, Bayerdörffer E, Lehn N, Stolte M.
Randomized trial of rifabutin-based triple therapy and high-dose dual therapy for rescue
treatment of Helicobacter pylori resistant to both metronidazole and clarithromycin. Aliment
Pharmacol Ther 2006;24:395-403.
Miehlke S, Menzel A, Brückner S, Aust D, Morgner A, Madisch A. Retrieval of two retained
endoscopy capsules by retrograde double-balloon enteroscopy in a patient with a long
history of small bowel disease. Endoscopy 2007; 39 Suppl 1:E157.
Madisch A, Miehlke S, Neuber F, Morgner A, Kuhlisch E, Seitz G, Rappel S, Lehn N,
Bayerdörffer E, Stolte M. Healing of lymphocytic gastritis after H. pylori eradication therapy-
a randomized, double-blind, placebo-controlled, multicenter trial. Aliment Pharmacol Ther
2006;23:473-9.
Madisch A, Miehlke S, Lindner M, Bethke B, Stolte M. Clinical course of collagenous colitis
over a period of 10 years. Z Gastroenterol 2006;44:971-974.

Lucke K, Miehlke S, Jacobs E, Schuppler M. Population shift in colonic mucosa-associated
microflora in ulcerative colitis. J Med Microbiol 2006;55:617-24.
Manner H, May A, Miehlke S, Dertinger S, Wigginghaus B, Schimming W, Krämer W,
Niemann G, Stolte M, Ell C. Ablation of nonneoplastic Barrett’s mucosa using argon plasma
coagulation with concomitant esomeprazole therapy (APBANEX): a prospective multicenter
evaluation. Am J Gastroenterol 2006;101:1762-9.
Morgner A, Labenz J, Miehlke S. Effective Regimes for the treatment of Helicobacter pylori
Infection. 2006;15:995-1016.
Trautmann K, Stolte M, Miehlke S. Helicobacter pylori eradication in prevention of gastric
cancer. World J Gastroenterol 2006;12:5101-7.
Kirsch C, Morgner A, Miehlke S. Relevance of cytochrome P450 polymorphism in the
treatment of Helicobacter pylori infection and gastroesophageal reflux disease. Current
Pharmacogenomics 2006;4:47-56.
, Endoscopy-Based Diagnosis and Treatment of Gastroesophageal Reflux Disease (GERD).

Madisch A, Hellmig S, Schreiber S, Bethke B, Stolte M, Miehlke S. NOD2/CARD15 gene
polymorphisms are not associated with collagenous colitis. Int J Colorect Dis 2006; Jun 28;
[Epub ahead of print].
, , , , Miehlke S,
, . Mucosal
FOXP3+ regulatory T cells are numerically deficient in acute and chronic GvHD.
Blood 2006;107:1717-23.
2005

Miehlke S, Madisch A, Voss C, Morgner A, Heymer P, Kuhlisch E, Bethke B, Stolte M. Long-
term follow-up of collagenous colitis after induction of clinical remission with budesonide.
Aliment Pharmacol Ther 2005;22:1115-9.
, . Time to remission with budesonide in
collagenous colitis. Aliment Pharmacol Ther 2005;21:1507-8.
Miehlke S, Madisch A, Kirsch C, Lindner F, Kuhlisch E, Laass M, Knoth H, Morgner A,
Labenz J. Intragastric acidity during treatment with esomeprazole 40 mg twice daily and
pantoprazole 40 mg twice daily – a randomized, two-way crossover study. Aliment
Pharmacol Ther 2005;21:963-7.
Madisch A, Miehlke S, Bayerdörffer E, Wiedemann B, Antos D, Sievert A, Vieth M, Stolte M,
Schulz H. Long-term follow-up after complete ablation of Barrett’s esophagus with argon
plasma coagulation. World J Gastroenterol 2005;11:1182-6.
Madisch A, Miehlke S, Labenz J. Management of functional dyspepsia: Unsolved problems
and new perspectives. World J Gastroenterol 2005;11:6577-81.
Halank M, Miehlke S, Kolditz M, Hoeffken G. Portopulmonale Hypertonie. Z Gastroenterol
2005;43:677-85.
Morgner-Miehlke A, Petersen, KU, Miehlke S, Labenz J. Review of Esomeprazole: potent
acid suppression in the treatment of acid related disorders. Exp Rev Clin Immunol 2005,1:
513-529.
Schwarz UI, Seemann D, Oertel R, Miehlke S, Kuhlisch E, Fromm MF, Kim RB, Bailey DG,
Kirch W. Grapefruit Juice Ingestion significantly reduces Talinolol Bioavailability. Clin
Pharmacol Ther 2005;77:291-301.
Trautmann K, Steudel C, Grossmann D, Aust D, Ehninger G, Miehlke S, Thiede C.
Expression profiling from gastric cancer samples by oligonucleotide micro array analysis
reveals low degree of intra-tumor variability. World J Gastroenterol 2005;11:5993-6.
Madisch A, Heymer P, Voss C, Wigginghaus B, Bästlein E, Bayerdörffer E, Meier E,
Schimming W, Bethke B, Stolte M, Miehlke S. Oral Budesonide therapy improves quality of
life in patients with collagenous colitis. Int J Colorect Dis 2005;20:312-6.

Miehlke S, Morgner A, Ehninger G. Gastric MALT lymphoma and gastrointestinal stromal
tumors. Schweiz Rundsch Med Praxis 2004;93:2143-50.
Krah A, Miehlke S, Pleissner KP, Zimny-Arndt U, Kirsch C, Lehn N, Meyer TF, Jungblut PR,
Aebischer T. Identification of candidate antigens for serologic detection of Helicobacter pylori
infected patients with gastric carcinoma. Int J Cancer 2004;108:456-63.
Morgner A, Miehlke S. Komplikationen der peptischen Ulkuskrankheit: Diagnostik und
Therapie der akuten nicht-varikösen oberen Gastrointestinalblutung. Medizin 200 plus
1/2004.
Madisch A, Miehlke S, Plein K, Hollerbach S.
Behandlungsmöglichkeiten bei funktioneller Dyspepsie. Der Mediziner, Ausgabe 3/2004.
Madisch A, Miehlke S, Plein K, Hollerbach S. Diagnosesicherung und
Behandlungsmöglichkeiten bei funktioneller Dyspepsie. Facharzt 2/2004.
Backert S, Schwarz T, Miehlke S, Kirsch C, Sommer C, Kwok T, Gerhard M, Goebel U, Lehn
N, König W, Meyer TF. Functional analysis of the cag pathogenicity island in Helicobacter
pylori
isolates from patients with gastritis, peptic ulcer and gastric cancer: Infect Immun
2004;72:1043-1056.
Jüttner S, Vieth M, Miehlke S, Schneider-Brachert W, Kirsch C, Pfeuffer T, Lehn, N, Stolte
M. Reliable detection of macrolid-resistant Helicobacter pylori via fluorescence in situ
hybridisation in formalin-fixed tissue. Mod Pathol 2004;17:684-9.
Kirsch C, Madisch A, Piehler P, Bayerdörffer E, Stolte M, Miehlke S. Helicobacter pylori in
gastritic corpus 20 years after partial gastric resection. World J Gastroenterol 2004;10:2560-
2.
2003

Miehlke S, Kirsch C, Schneider-Brachert W, Haferland C, Neumeyer M, Bästlein E, Vieth M,
Stolte M, Lehn N, Bayerdörffer E. A prospective, randomized study of quadruple therapy and
high-dose omeprazole/amoxicillin therapy for treatment of Helicobacter pylori resistant to
both metronidazole and clarithromycin. Helicobacter 2003;8:310-319.
Miehlke S, Schneider-Brachert W, Bästlein E, Ebert S, Kirsch C, Haferland C, Buchner M,
Neumeyer M, Vieth M, Stolte M, Lehn N, Bayerdörffer E. One-week triple therapy with
esomeprazole, clarithromycin and metronidazole is effective in eradicating Helicobacter
pylori
in the absence of antimicrobial resistance. Aliment Pharmacol Ther 2003;18:799-804.
Miehlke S. Helicobacter pylori and gastric carcinogenesis. In: Disease Progession and
Carcinogenesis in the Gastrointestinal Tract. Eds. P. Galle et al. Kluwer Academic
Publishers, Dordrecht, Boston, London, November 2003.
Madisch A, Kulich KR , Malfertheiner P, Ziegler K, Bayerdörffer E, Miehlke S, Labenz J,
Carlsson J, Wiklund IK. Burden of Illness in Patients with Reflux Disease – Evidence from a
Recent Comparative Methodological Study in Germany. Z Gastroenterol 2003;41:1137-1143.
Kulich KR, Malfertheiner P, Madisch A, Labenz J, Bayerdorffer E, Miehlke S, Carlsson J,
Wiklund IK. Psychometric validation of the German translation of the Gastrointestinal
Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD)
questionnaire in patients with reflux disease. Health and Quality of Life Outcomes 2003,1:62.
Smith S, Lück PC, Bayerdörffer E, Miehlke S. Genotyping of Nigerian Helicobacter pylori
isolates by pulsed-field gel electrophoresis. J Med Microbiol 2003;52:931.
Smith SI, Chibututu C, Anomneze E, Atimomo C, Atoyebi O, Ndububa D, Agbakwuru A,
Bayerdörffer E, Miehlke S. Molecular typing of Nigerian Helicobacter pylori isolates by glmM
restriction fragment length polymorphism. Br J Biomed Sci 2003;60:170-2.
2002

Miehlke S, Heymer P, Bethke B, Bästlein E, Meier E, Bartram HP, Wilhelms G, Lehn N,
Dorta G, DeLarive J, Tromm A, Bayerdörffer E, Stolte M. Budenoside treatment for
collagenous colitis – a randomized, double-blind, placebo-controlled, multicenter trial.
Gastroenterology 2002;123:978-84.
Miehlke S, Yu J, Ebert M, Szokodi D, Vieth M, Kuhlisch E, Buchcik R, Schimming W,
Wehrmann U, Malfertheiner P, Stolte M, Ehninger G, Bayerdörffer E. Expression of G1
phase cyclins in human gastric cancer, intestinal metaplasia, and in the gastric mucosa of
first degree relatives. Dig Dis Sci 2002;47:1248-56.
Smith SI, Miehlke S, Oyedeji KS, Arigbabu AA, Coker AO. Fingerprinting of Nigerian
Helicobacter pylori Isolates by plasmid profile and PCR. J Basic Microbiol 2002;1:45-53.

Meining A, Wick M, Miehlke S, Bayerdörffer E, Stolte M, Sackmann M, Ochsenkühn T. The
presence of immunoglobulins in the gastric juice of patients infected with Helicobacter pylori
is related to a reduced secretion of acid. Helicobacter 2002;7:67-70.

Stolte M, Meining A, Miehlke S, Bayerdörffer E. Progress in understanding of H. pylori
infection and gastritis. In: Helicobacter pylori – Basic Mechanisms to Clinical Cure 2002, Eds.
R.H. Hunt, G.N.J. Tytgat, Kluwer Academic Publishers, Dordrecht, Boston, London,
November 2002.
Smith SI, Kirsch C, Oyedeji KS, Arigbabu AO, Coker AO, Bayerdöffer E, Miehlke S.
Prevalence of Helicobacter pylori vacA, cagA, and iceA genotypes in Nigerian patients with
duodenal ulcer disease. J Med Microbiol 2002 ;51:851-4.
Smith S, Cantet F, Angelini F, Marais A, Megraud F, Bayerdoffer E, Miehlke S.
Discriminatory power of RAPD, PCR-RFLP and southern blot analyses of ureCD or ureA
gene probes on Helicobacter pylori isolates. Z Naturforsch 2002;57:516-21.
2001
Miehlke S
, Yu J, Schuppler M, Frings C, Kirsch C, Negraszus N, Morgner A, Stolte M,
Ehninger G, Bayerdörffer E. Helicobacter pylori vacA, iceA, and cagA status, and pattern of
gastritis in patients with malignant and benign gastroduodenal disease. Am J Gastroenterol
2001,96:1008-13.
Miehlke S, Kirsch C, Dragosics B, Gschwantler M, Oberhuber G, Antos D, Dite P, Läuter J,
Labenz J, Leodolter A, Malfertheiner P, Neubauer A, Ehninger G, Stolte M, Bayerdörffer.
Helicobacter pylori and Gastric Cancer: Current Status of the Austrian-Czech-German
Gastric Cancer Prevention Trial (PRISMA-Study). World J Gastroenterol 2001;7:243-7.

Miehlke S, Bayerdörffer E, Graham DY. Treatment of H. pylori infection. Seminars in
Gastrointestinal Diseases 2001;12:167-79.
Miehlke S, Bayerdörffer E, Ehninger G, Stolte M. Präkanzeröse Risikomarker der
Helicobacter pylori
-Gastritis. Pathologe 2001,22:31-6.
Morgner A, Miehlke S, Fischbach WK, Schmitt W, Müller-Hermelink HK, Greiner A, Thiede
C, Schetelig J, Neubauer A, Stolte M, Ehninger G, Bayerdörffer E. Complete remission of
primary high-grade B-cell gastric lymphoma after cure of Helicobacter pylori infection. J Clin
Oncol 2001;19:2041-8.
Morgner A, Miehlke S, Bayerdörffer E, Neubauer A, Thiede C, Klann H, Hierlmeier FX,
Ehninger G, Stolte M. Development of early gastric cancer 4 years after complete remission
of Helicobacter pylori-assoiated gastric low-grade B-cell MALT lymphoma. World J
Gastroenterol 2001;248-53.
Meining A, Morgner A, Miehlke S, Bayerdörffer E, Stolte M. Atrophy-metaplasia-dysplasia-
carcinoma sequence in the stomach: a reality or merely an hypothesis? Best Pract Res Clin
Gastroenterol 2001;15:983-98.


2000

Miehlke S, Kirsch C, Agha-Amiri K, Günther T, Lehn N, Malfertheiner P, Stolte M, Ehninger
G, Bayerdörffer E. The Helicobacter pylori vacA s1;m1 genotype and cagA is associated with
gastric carcinoma in Germany. Int J Cancer 2000; 87:322-7.
Schulz H, Miehlke S, Antos D, Vieth M, Schentke KU, Stolte M, Bayerdörffer E. Ablation of
Barrett’s epithelium by endoscopic argon plasma ablation combined with high-dose
omeprazole treatment. Gastrointest Endosc 2000;51:659-63.
Yu J, Miehlke S, Ebert MP, Hoffmann J, Breidert M, Alpen B, Starzynska T, Stolte M,
Malfertheiner P, Bayerdörffer E. Frequency of TPR-MET rearrangement in patients with
gastric carcinoma and in first-degree relatives. Cancer 2000;88:1801-6.
Ebert M, Yu J, Miehlke S, Lendeckel U, Neubauer A, Stolte M, Bayerdörffer E, Malfertheiner
P. Expression of transforming growth factor beta-1 in gastric cancer and in the gastric
mucosa of first-degree relatives of patients with gastric cancer. Brit J Cancer 2000;82:1795-
800.
Yu J, Ebert MP, Miehlke S, Rost H, Lendeckel U, Leodolter A, Stolte M, Bayerdorffer E,
Malfertheiner P. Alpha-catenin expression is decreased in human gastric cancers and in the
gastric mucosa of first degree relatives. Gut 2000;46:639-44.
Ebert MP, Günther T, Hoffmann J, Yu J, Miehlke S, Schulz HU, Roessner A, Korc M,
Malfertheiner P. Expression of metallothionein II in intestinal metaplasia, dysplasia, and
gastric cancer. Cancer Res 2000;60:1995-2001.
1999

Miehlke S, Genta RM, Graham DY, Go MF. Molecular relationships of Helicobacter pylori
strains in a family with gastroduodenal disease. Am J Gastroenterol 1999;94:364-368.

Miehlke S
, Thomas R, Guiterrez O, Graham DY, Go MF. DNA fingerprinting of single
colonies of Helicobacter pylori from gastric cancer patients suggests infection with a single
predominant strain. J Clin Microbiol 1999;137:245-247.

Miehlke S, Bayerdörffer E, Malfertheiner P. Treatment of Helicobacter pylori reinfection. In:
Scarpignato C, Bianchi Porro G (eds.): Clinical pharmacology & therapy of Helicobacter
pylori
infecion. Prog Basic Clin Pharmacol. Basel. Karger 1999;11:346-52.
Breidert M, Miehlke S, Orban Z, Glasow A, Stolte M, Ehninger G, Bayerdörffer E,
Nettesheim O, Halm U, Haidan A, Bornstein SR. Leptin and its receptor in normal human
gastric mucosa and in Helicobacter pylori gastritis. Scand J Gastroenterol 1999;34:954-961.
Lucke K, Miehlke S, Schuppler M. Comparative 16S rRNA analysis of the colorectal
mucosa-associated bacterial flora in patients with ulcerative colitis. Hygiene Mikrobiologie
1999;3:24-5.
Bayerdörffer E, Miehlke S, Labenz J, Dragosics B, Läuter J, Neubauer A, Malfertheiner P,
Stolte M. Magenkarzinomprophylaxe durch Helicobacter pylori -Eradikation? - Einladung zur
Teilnahme an der PRISMA-Studie. Z Gastroenterol 1999;37:XXI-XXV.
Bayerdörffer E, Miehlke S, Labenz J, Stolte M, Malfertheiner P. Prävention des
Magenkarzinoms. Ist eine Eradikation von Helicobacter pylori sinnvoll? Deutsches Ärzteblatt
1999;96:A-1786-1788.
Breidert M, Miehlke S, Gillespie J, Ehninger G, Bornstein SR. Die Laser Capture
Mikrodissektion: moderne Analyse molekulargenetischer Alterationen.
Onkologe 1999;5:170-2.
Gerhard M, Lehn N, Neumayer N, Boren T, Rad R, Schepp W, Miehlke S, Classen M, Prinz
C. Clinical relevance of the Helicobacter pylori gene for blood group antigen binding adhesin.
Proc Natl Acad Sci 1999,96:12778-83.
1998

Miehlke S, Go MF, Kim JG, Graham DY, Figura N. Serologic detection of Helicobacter pylori
infection with cagA+ strains in duodenal ulcer, gastric cancer, and asymptomatic gastritis J
Gastroenterol 1998;33:18-21.
Miehlke S, Hackelsberger, Meining A, Hatz R, Lehn N, Malfertheiner P, Stolte M,
Bayerdörffer E. Severe expression of corpus gastritis is characteristic in gastric cancer
patients infected with Helicobacter pylori. Brit J Cancer 1998;78:263-266.
Miehlke S, Meining A, Lehn N, Höchter W, Weingart J, Simon T, Krämer W, Klann H, Bolle
KH, Sommer A, Stolte M, Bayerdörffer E. Comparison of omeprazole, metronidazole and
clarithromycin with omeprazole/amoxicillin dual therapy for the cure of Helicobacter pylori
infection. Digestion 1998;59:646-650.
Miehlke S, Meining A, Morgner A, Bayerdörffer E, Lehn N, Stolte M, Graham DY, Go MF.
Frequency of vacA genotypes and cytotoxin activity in Helicobacter pylori associated with
gastric MALT-lymphoma. J Clin Microbiol 1998; 36:2369-2370.
Miehlke S, Bayerdörffer E, Malfertheiner P. Helicobacter pylori Infektion und die Entwicklung
von Magenneoplasien. Verdauungskrankheiten 1998;16:77-83.
Stolte M, Bayerdörffer E, Miehlke S, Meining A, Dragosics B, Oberhuber G, Malfertheiner P.
Helicobacter pylori -Eradikation zur Prophylaxe des Magenkarzinoms - Einladung zur
deutsch-österreichischen PRISMA-Studie. Leber Magen Darm 1998;28:128-135.
Meining A, Stolte M, Müller P, Miehlke S, Lehn N, Hölzel D, Bayerdörffer E. Gastric
carcinoma risk index in patients infected with Helicobacter pylori. Virchows Arch
1998;432:311-314.
Schulzte V, Hackelsberger A, Günther T, Miehlke S, Roessner A, Malfertheiner P. Differing
patterns of Helicobacter pylori gastritis in patients with duodenal, prepyloric and gastric ulcer
diseases. Scand J Gastroenterol 1998;33137-142.
Stolte M, Bayerdörffer E, Meining A, Miehlke S, Malfertheiner P. Helicobacter pylori und
Magenkarzinom - Ist eine präventive Interventionsstudie sinnvoll? Pathologe 1998; 19:330-
334.
1997

Miehlke S, Mannes GA, Lehn N, Bayerdörffer E, Hele C, Stolte M. An increasing dose of
omeprazole combined with amoxicillin cures Helicobacter pylori infection more effectively.
Aliment Pharmacol Ther 1997;11:323-329.
Miehlke S, Hackelsberger A, Meining A, v. Arnim U, Müller P, Ochsenkühn T, Lehn N,
Malfertheiner P, Stolte M, Bayerdörffer E. Histological diagnosis of Helicobacter pylori
gastritis predicts is predictive of high risk of gastric carcinoma. Int J Cancer 1997, 73:837-39.

Miehlke S
, Graham DY. Antimicrobial therapy of peptic ulcers. International Journal of
Antimicrobial Agents 1997;8:171-78.
Miehlke S, Bayerdörffer E, Meining A, Stolte M, Malfertheiner P. Identifying persons at risk
for gastric cancer? Helicobacter 1997;2:S61-S66.
Bayerdörffer E, Miehlke S, Neubauer A, Stolte M. Gastric MALT lymphoma and Helicobacter
pylori
Infection. Aliment Pharmacol Ther 1997;11:89-94.
Malfertheiner P, Miehlke S. Helicobacter pylori infection in ulcer pathogenesis. Digestion
1997;58:17-20.
Meining A, Stolte M, Hatz R, Lehn N, Miehlke S, Morgner A, Bayerdörffer E. Differing degree
and distribution of gastritis in Helicobacter pylori associated diseases. Virchows Arch 1997,
431:11-15.
1996

Miehlke S, Bayerdörffer E, Lehn N, Mannes GA, Sommer A, Höchter W, Weingart J,
Heldwein W, Hatz R, Stolte M. Severity of Helicobacter pylori gastritis predicts duodenal
ulcer recurrence. Scand J Gastroenterol 1996;31:856-862.
Miehlke S, Kibler K, Kim JG, Figura N, Small SM, Graham DY, Go MF. Allelic variation in
Helicobacter pylori cagA gene from Korea compared to the United States. Am J
Gastroenterol 1996;91:1322-1325.

Miehlke S, Osato M, Reddy R, Wood P, Conneely O, Graham DY. Direct antibacterial
activity of recombinant human lactoferrin against Helicobacter pylori. J Clin Microbiol
1996;34:2593-94.
Miehlke S, Bayerdörffer E, Lehn N, Meining A, Bästlein E, Mannes GA, Stolte M.
Helicobacter pylori reinfection is rare in peptic ulcer patients cured by antimicrobial therapy.
Eur J Gastroenterol 1996; 8:1161-63.
Miehlke S, Malfertheiner P. Ulkuspathogenese: Die Rolle von Helicobacter pylori. Zeitschrift
für Allgemeinmedizin 1996;72: 668-671.
Bayerdörffer E, Miehlke S, Lehn N, Mannes GA, Höchter W, Weingart J, Klann H, Sommer
A, Heldwein W, Hatz R, Simon T, Bolle KH, Bästlein E, Meining A, Ruckdeschel G, Stolte M.
Cure of gastric ulcer disease after cure of Helicobacter pylori infection. Eur J Gastroenterol
1996;8:343-349.
1995

Miehlke S, Bayerdörffer E, Lehn N, Mannes GA, Sommer A, Höchter W, Weingart J,
Bästlein E, Hatz R, Ruckdeschel G, Dirschedl P, Stolte M. Two-year follow-up of duodenal
ulcer patients after treatment with omeprazole and amoxicillin. Digestion 1995;56:187-193.
Miehlke S, Bayerdörffer E, Lehn N, Mannes GA, Höchter W, Weingart J, Sommer A,
Heldwein W, Ruckdeschel G, Köpke W, Stolte M. Recurrence of duodenal ulcers during a
five-year follow-up after cure of Helicobacter pylori infection. Eur J Gastro Hepatol
1995;7:975-978.
Bayerdörffer E, Miehlke S, Lehn N, Mannes GA, Sommer A, Höchter W, Heldwein W,
Weingart J, Klann H, Simon T, Schmitt W, Bästlein E, Eimiller A, Hatz R, Dirschedl P, Stolte
M. Double blind trial of omeprazole and amoxicillin to cure Helicobacter pylori infection in
patients with duodenal ulcers. Gastroenterology 1995,108:1412-1417.
Bayerdörffer E, Miehlke S, Mannes GA. Indikationen und Therapieempfehlungen zur
Helicobacter pylori-Eradikation. Der Bayerische Internist 1995;15:64-70.
1994

Bayerdörffer E, Miehlke S, Mannes GA. Helicobacter pylori-Eradikationstherapie mit
Omeprazol und Amoxicillin: Heutiger Stand. Leber Magen Darm 1994;24:228-232.
Bayerdörffer E, Miehlke S, Mannes GA. Eradikationstherapie beim Ulcus duodeni:
Ergebnisse, Indikation und Therapieempfehlungen. Gastro-Liga Report 1994;3/4:15-19.
1993

Bayerdörffer E, Miehlke S, Lehn N, Mannes GA, Sommer A, Höchter W, Hatz R, Stolte M.
Chronic type B-gastritis as an important denominator of peptic ulcer healing. Eur J
Gastroenterol Hepatol 1993;5: 99-105.

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