Avdeling for helsefag i Namsos Fag/enhet: Eksamenskode: Galenisk Farmasi II Dag og dato: Tirsdag, 04.12.2007 Tid (fra – til): kl 09.00-15.00 Eksamen Galenisk Farmasi 2 Oppgave 1 Fentanyl er et sterkt opioidanalgetikum som brukes mot veldig sterke smerter og i sammenheng med kirurgiske inngrep. I Norge finnes tre legemiddelformer, bl.a. en sugetablettformuler
Ryanspet.comMATERIAL SAFETY DATA SHEET
ZODIAC® GROOMERS’ SPOT ON PACK
Manufacturer: Wellmark International
Address: 1501 E. Woodfield Rd., Suite 200-West, Schaumburg, IL 60173
Emergency Phone: 1-800-950-4783
Transportation Emergency Phone: CHEMTREC: 1-800-424-9300
1. CHEMICAL PRODUCT INFORMATION
Product Name: Zodiac® Groomers’ Spot On Pack
Chemical Name/Synonym: (S)-Methoprene: Isopropyl (2E,4E,7S)-11-methoxy-3,7,11-trimethyl-2,4-
Chemical Family: Terpenoid
Formula: C19 H34 03
EPA Registration No.: 2724-497
RF Number: 9908
2. COMPOSITION / INFORMATION ON INGREDIENTS
Component (chemical, common name)
(S)-Methoprene: Isopropyl (2E,4E,7S)-11-methoxy-3,7,11-trimethyl-
Inert ingredients (non hazardous and/or trade secret)
3. HAZARD INFORMATION
CAUTION: KEEP OUT OF THE REACH OF CHILDREN
Hazards to Humans: Avoid contact with eyes, skin, or clothing. Wash thoroughly with soap
and water after handling.
SYMPTOMS OF OVER EXPOSURE
Acute dermal or oral exposure may cause CNS effects such as headache and nausea.
PRIMARY ROUTE OF ENTRY
Dermal/Eye: Y Yes
LD50 Combined >5.0 g/kg - Tox Category IV OTHER TOXICOLOGICAL INFORMATION
Skin Irritation: May cause minor skin irritation
Eye Irritation: May cause minor eye irritation
Sensitizer: Not a Contact Sensitizer
4. FIRST AID MEASURES
Eye: Hold eyes open and rinse slowly and gently with water for 15-20 minutes.
Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eyes. Skin: Take off contaminated clothing. Rinse skin immediately with plenty of water for
15 –20 minutes. Call poison control center or Dr. for treatment advice. Ingestion: Call physician. Do not induce vomiting or give anything by mouth if person is
Inhalation: Remove individual to fresh air. If breathing does not return to normal within
a few minutes, get medical attention immediately. If breathing is difficult, Note to Physician: N/A
Information: Have the product container or label with you when calling a poison control
center or doctor or going for treatment . May also contact 1-800-950-4783 or a poison control center for treatment advice. 5. FIRE FIGHTING MEASURES
Rating: Health: 2
Flammability Class: Combustible
Flash Point: 131°F
Explosive Limits (% of Volume): Unknown
Extinguishing Media: Water, CO2 dry chemicals, foam
Special Protective Equipment: Firefighters should wear full protective clothing including self-contained
Fire Fighting Procedures: Normal procedures. Do not allow fire fighting water to escape into water-ways
Combustion Products: Carbon dioxide and carbon monoxide
Unusual Fire/Explosion Hazards: Large Quantities: Vapors may travel along the ground or be moved by
Ventilation and ignited by heat, pilot lights, other flames and ignition sources at locations distant from material handling point. Never use welding or cutting torch near product. Product may ignite easily. 6. ACCIDENTAL RELEASE MEASURES
Steps to be taken: Do not allow spill to enter water ways inhabited by aquatic organisms. Soak up
with absorbent material and place in a suitable container for disposal. Absorbents: Clay granules, dirt, or equivalent.
Incompatibles: Strong oxidizing agents.
7. HANDLING AND STORAGE
Avoid eye contact. Wash hands after handling. Storage: Do not contaminate water, food, or feed by storage. Store in a dry, cool place
8. EXPOSURE CONTROL / PERSONAL MEASURES
Exposure Limits: Not Established
Ventilation: General ventilation is sufficient.
Personal Protective Equipment: Not needed if product is used according to label. If prolonged exposure is
anticipated, wear impervious gloves and safety glasses or goggles. 9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance and Odor: Light amber liquid
Boiling Point: 392F
Melting Point: N/A
Vapor Pressure (mm Hg): N/A
Vapor Density (Air = 1): ›1
Specific Gravity: 1.03
Bulk Density: 8.612 pounds/gallon
Evaporation Rate: N/A
10. STABILITY AND REACTivITY
Reactivity: Not determined
Incompatibility w/ Other Avoid contact with strong oxidizing agents
Decomposition Products: Not determined
Hazardous Polymerization: Will not occur
11. TOXICOLOGICAL INFORMATION
CHRONIC TOXICITY[Based on (RS)-Methoprene Technical]
Methoprene is not considered a carcinogenic compound. Permethrin is not considered a carcinogenic compound.
DEVELOPMENTAL/REPRODUCTIVE TOXICITY [Based on (RS)-Methoprene Technical ]
Methoprene is not a teratogenic compound. Permethrin is not a teratogenic compound.
MUTAGENICITY [Based on (S)-Methoprene Technical]
Methoprene is not a mutagenic compound. Permethrin is not a mutagenic compound.
12. ECOLOGICAL INFORMATION
(RS) Methoprene Technical
Hydrolysis: T1/2 > 4 weeks ~ 20 days
Photolysis: T1/2 < 10 hours ~ 10 hours
Soil half life: ∼ 10 days ~ 4 Weeks
Water solubility: < 2 ppm ~ 0.04 ppm
Acute Toxicity: This product is toxic to fish.
(S) Methoprene Technical: LC50 (trout): 760ppb, (Bluegill): >370ppb;
aquatic invertebrates: LC50 (Daphnia): 360 ppb
Permethrin Technical: 1.4 to 7.9 mg/1L (trout)
13. DISPOSAL CONSIDERATIONS
Disposal: If Empty: Do not reuse empty applicator. Place in trash and offer for recycling if available.
If Partly Filled: Call your local solid waste agency or 1-800-CLEANUP for disposal instructions.
Never place unused product down any indoor or outdoor drain.
14. TRANSPORT INFORMATION
DOT49CFR Description: Not regulated via highway and rail.
Freight Classification: Animal Insecticides N.O.I. O/T Poison.
15. REGULATORY INFORMATION
CERCLA (Superfund): Not Listed
RCRA: Not Regulated
SARA 311/312 HAZARD CATEGORIES
Sara Title, Section313:
Cas number: 52645-53-1 Ingredient Name: Permethrin Percent by weight: Min: 2.375% Max: 2.625%
Immediate Health: Yes (irritant)
Delayed Health: No
Sudden Pressure: No
The information presented herein, while not guaranteed, was prepared by technically knowledgeable personnel and to the best of our knowledge is true and accurate. It is not intended to be all inclusive and the manner and conditions of use and handling may involve other or additional considerations.
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