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Safety Data Sheet
Tetracycline

1. PRODUCT AND COMPANY IDENTIFICATION


Product Name:
Tetracycline

Synonyms/Generic Names: 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12aoctahydro-3,6,10,12,12a-
pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride
SDS Number: 753.00
Product Use: For Educational Use Only
Manufacturer: Columbus Chemical Industries, Inc.

For More Information Contact: Ward's Science
5100 West Henrietta Rd. PO Box 92912-9012 Rochester, NY 14692 (800) 962-2660 (Monday-Friday 7:30-7:00 Eastern Time) In Case of Emergency Call: CHEMTREC - 800-424-9300 or 703-527-3887 (24 Hours/Day, 7 Days/Week)

2. HAZARDS IDENTIFICATION
OSHA Hazards:
Target organ effect, Irritant
Target Organs: Liver, Teeth, Bone
Signal Word: Warning
Pictograms:
GHS Classification:

Specific target organ toxicity - single exposure
GHS Label Elements, including precautionary statements:

Hazard Statements:
Precautionary Statements:
Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. Wear protective gloves/ eye protection/ face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove victim to fresh air and keep at rest in a position P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Potential Health Effects

Inhalation
May be harmful if inhaled. Causes respiratory tract irritation. May be harmful if absorbed through skin. Causes skin irritation. Ingestion

NFPA Ratings

HMIS Ratings
Flammability
Reactivity
Reactivity
Specific hazard
Personal


3. COMPOSITION/INFORMATION ON INGREDIENTS

EINECS# /
Molecular
Component
C22H24N2O8 · HCl
4. FIRST-AID MEASURES
Rinse with plenty of water for at least 15 minutes and seek medical attention if necessary. Inhalation
Move casualty to fresh air and keep at rest. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention if necessary. Flush with plenty of water and wash using soap. Get medical attention if necessary. Ingestion
Do Not Induce Vomiting! Never give anything by mouth to an unconscious person. If
conscious, wash out mouth with water. Get medical attention if necessary.

5. FIRE-FIGHTING MEASURES

Suitable (and unsuitable)
Product is not flammable. Use appropriate media for adjacent fire. Cool extinguishing media
Special protective equipment
Wear self-contained, approved breathing apparatus and full protective and precautions for firefighters
clothing, including eye protection and boots. Specific hazards arising from
Emits toxic fumes (carbon oxides, hydrogen chloride gas, nitrogen the chemical
oxides) under fire conditions. (See also Stability and Reactivity section).
6. ACCIDENTAL RELEASE MEASURES

Personal precautions,
See section 8 for recommendations on the use of personal protective protective equipment and
emergency procedures
Environmental precautions
Prevent spillage from entering drains. Any release to the environment may be subject to federal/national or local reporting requirements. Methods and materials for
Pick up and arrange disposal without creating dust. Sweep up and place containment and cleaning up
in suitable, closed containers for disposal. Clean surfaces thoroughly with water to remove residual contamination. Dispose of all waste and cleanup materials in accordance with regulations.
7. HANDLING AND STORAGE
Precautions for safe handling
See section 8 for recommendations on the use of personal protective equipment. Use with adequate
ventilation. Wash thoroughly after using. Keep container closed when not in use. Avoid formation of dusts.
Conditions for safe storage, including any incompatibilities
Store in cool, dry well ventilated area. Keep away from incompatible materials (see section 10 for
incompatibilities).
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Occupational exposure controls:
Contains no substances with occupational exposure limit values.
Personal Protection
Wear chemical safety glasses or goggles. Inhalation
Provide local exhaust, preferably mechanical. If exposure levels are excessive, use an approved respirator. Wear nitrile or rubber gloves, apron or lab coat.
Other Recommendations
Provide eyewash stations, quick-drench showers and washing facilities accessible to areas of use and
handling.

9. PHYSICAL AND CHEMICAL PROPERTIES

Appearance (physical state, color, etc.) Upper/lower flammability or explosive limit
10. STABILITY AND REACTIVITY

Chemical Stability
Possibility of Hazardous Reactions
Conditions to Avoid
Incompatible Materials
Hazardous Decomposition Products
Carbon oxides, nitrogen oxides, hydrogen chloride gas.
11. TOXICOLOGICAL INFORMATION
Acute Toxicity

Respiratory
Ingestion

Carcinogenicity

No components of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. No components of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH. No components of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP. No components of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA.
Signs & Symptoms of Exposure

Irritation, redness, watering eyes, itchiness. Respiratory
Ingestion
Irritation, nausea, vomiting, diarrhea, phototoxic reactions, yellowing of teeth, reduced mineralization. Chronic Toxicity
The substance is toxic to the reproductive system, liver. Teratogenicity
Mutagenicity
Embryotoxicity
Specific Target Organ Toxicity
Inhalation - May cause respiratory irritation. Reproductive Toxicity
Respiratory/Skin Sensitization
Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals.
12. ECOLOGICAL INFORMATION
Ecotoxicity

Aquatic Vertebrate
LC50 - Salvelinus namaycush - 220 mg/l - 96 h Aquatic Invertebrate Not Available
Terrestrial
Persistence and Degradability
Bioaccumulative Potential
Mobility in Soil
PBT and vPvB Assessment
Other Adverse Effects

13. DISPOSAL CONSIDERATIONS

Waste Residues
Users should review their operations in terms of the applicable federal/national or local regulations and consult with appropriate regulatory agencies if necessary before disposing of waste products or residues. Users should review their operations in terms of the applicable federal/national or Containers
local regulations and consult with appropriate regulatory agencies if necessary before disposing of waste product container.
The information offered in section 13 is for the product as shipped. Use and/or alterations to the product may
significantly change the characteristics of the material and alter the waste classification and proper disposal
methods.

14. TRANSPORTATION INFORMATION


15. REGULATORY INFORMATION

All ingredients are listed on the TSCA inventory. All ingredients are listed on the DSCL inventory. Class D-2A: Material causing other toxic effects (VERY TOXIC).
16. OTHER INFORMATION

Disclaimer: Columbus Chemical Industries, Inc. (“Columbus”) believes that the information herein is factual but is not intended to be all inclusive. The information relates only to the specific material designated and does not relate to its use in combination with other materials or its use as to any particular process. Because safety standards and regulations are subject to change and because Columbus has no continuing control over the material, those handling, storing or using the material should satisfy themselves that they have current information regarding the particular way the material is handled, stored or used and that the same is done in accordance with federal, state and local law. COLUMBUS MAKES NO WARRANTY, EXPRESS OR IMPLIED, INCLUDING (WITHOUT LIMITATION) WARRANTIES WITH RESPECT TO THE COMPLETENESS OR CONTINUING ACCURACY OF THE INFORMATION CONTAINED HEREIN OR WITH RESPECT TO FITNESS FOR ANY PARTICULAR USE.

Source: https://www.wardsci.com/stibo/hi_res/10607888.pdf

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